Research at the MRC Mitochondrial Biology Unit is focussed on the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases, and even, perhaps, in the process of ageing. Our Unit has three major scientific aims: To understand the fundamental processes taking place in mitochondria To understand the involvement of these processes in human diseases To exploit knowledge of these fundamental processes for the development of new therapies to treat human diseases Today, our Unit has nine independent research groups (described on this website). Their activities are focussed on understanding the fundamental biochemical and biological processes which occur in mitochondria. Via collaborations with clinical colleagues in several countries, we are building on our fundamental knowledge to try to understand how mitochondrial dysfunction leads to human disease. In addition, we are engaged in collaborations with pharmaceutical companies, to exploit our fundamental knowledge to generate new therapies.