PolyBio Research Foundation is a 501(c)3 transforming how complex chronic conditions like LongCOVID, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and LongLyme disease are studied, diagnosed, and treated. PolyBio conceptualizes research projects that identify root cause drivers of chronic conditions and builds collaborative teams to make the projects a reality. The LongCovid Research Consortium (LCRC), an initiative of PolyBio, is a global scientific collaboration to rapidly and openly study core biological drivers of LongCOVID and channel insights to treatment innovation and clinical trials. The collaboration includes scientists and clinicians sharing ideas and samples across dozens of different institutions, laboratories, and clinics.