The 5-year long project called ‘PRIME’ (Prevention and Remediation of Insulin Multimorbidity in Europe) aims to unravel how brain disorders throughout life can be traced to alterations in insulin signalling and how this relates to the somatic diseases type 2 diabetes and obesity. In total, 17 different university and private sector groups from 9 different European countries will participate in PRIME, which will receive €6 million funding from the EU’s Horizon 2020 programme.