https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2025-0172
Announcing a new article publication for
BIO Integration journal. This review summarizes recent advances in the application of graphene oxide (GO) in sports medicine with an emphasis on cartilage repair, skeletal muscle regeneration, ligament and tendon repair, and tendon–bone (enthesis) healing. Owing to the distinctive physicochemical properties and favorable biocompatibility, GO exhibits considerable promise across these indications. The chemical structure and physical characteristics of GO are outlined then the mechanistic roles that underpin the performance of GO in different disease contexts are discussed. Evidence that GO strengthens biomaterials mechanically and enhances cellular adhesion and lineage commitment, which promotes tenogenic, chondrogenic, and myogenic differentiation. as well as enthesis formation are synthesized. Despite these advantages, important questions remain regarding the biosafety and long-term
in vivo stability of GO. Future work should prioritize rational chemical functionalization and composite design to tailor GO-based materials to specific tissue-repair requirements with the development of next-generation GO scaffolds that better recapitulate the human biomechanical milieu. In parallel, multi-omics interrogation of GO–cell interactions will deepen our mechanistic understanding and guide material optimization. Addressing these key challenges will enable GO to have a larger role in cartilage repair and sports medicine, accelerating progress in the field.
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BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine.
As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience,
BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.
Please visit
www.bio-integration.org to learn more about the journal.
Editorial Board: https://bio-integration.org/editorial-board/
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https://www.scienceopen.com/search#collection/55f45bac-fd64-431c-9fe7-50fd6a7f8781).
Submissions may be made using
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https://mc04.manuscriptcentral.com/bioi).
There are no author submission or article processing fees.
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ISSN 2712-0074
eISSN 2712-0082
Mengran Xi, Renwen Wan and Wei Luo et al. Graphene Oxide–based Biomaterials in Sports Medicine.
BIOI. 2026. Vol. 7(1). DOI: 10.15212/bioi-2025-0172
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