Harnessing Cell Membrane-Derived Nanovesicles for Enhanced Nanoprobes in Multimodal Imaging: Progress and Perspectives
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Harnessing Cell Membrane-Derived Nanovesicles for Enhanced Nanoprobes in Multimodal Imaging: Progress and Perspectives

22/10/2025 Compuscript Ltd
https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2025-0047
Announcing a new article publication for BIO Integration journal. Cell membrane-derived nanovesicles (CMNVs) are natural nanocarriers efficiently encapsulating bioactive molecules and imaging probes. Conventional nanoprobes face challenges, like rapid immune clearance, off-target accumulation, and long-term toxicity. CMNVs overcome these challenges by leveraging inherent biofunctionalization. CMNVs enhance encapsulated nanoprobe targeting, prolong circulation, boost specific tissue accumulation, and improve imaging precision through inherited membrane proteins or minimally disruptive exogenous modifications. CMNVs show significant promise across multiple imaging modalities, including fluorescence, bioluminescence, photoacoustic, and MRI. This article systematically evaluates the limitations of traditional nanoprobes, highlights the unique advantages of CMNVs in enhancing diverse probe performance, discusses current challenges in harnessing CMNVs for imaging, and provides insights for developing future high-precision imaging strategies.
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BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine.

As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.

Please visit www.bio-integration.org to learn more about the journal.
Editorial Board: https://bio-integration.org/editorial-board/

BIOI is available on the ScienceOpen platform (https://www.scienceopen.com/search#collection/55f45bac-fd64-431c-9fe7-50fd6a7f8781).

Submissions may be made using ScholarOne (https://mc04.manuscriptcentral.com/bioi).
There are no author submission or article processing fees.

Follow BIOI on Twitter @JournalBio; Facebook (https://www.facebook.com/BIO-Integration-Journal-108140854107716/) and LinkedIn (https://www.linkedin.com/company/bio-integration-journal/).

ISSN 2712-0074
eISSN 2712-0082

Lingling Lei, Meng Du and Jianjian Zhang et al. Harnessing Cell Membrane-Derived Nanovesicles for Enhanced Nanoprobes in Multimodal Imaging: Progress and Perspectives. BIOI. 2025. Vol. 6(1). DOI: 10.15212/bioi-2025-0047
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Lingling Lei, Meng Du and Jianjian Zhang et al. Harnessing Cell Membrane-Derived Nanovesicles for Enhanced Nanoprobes in Multimodal Imaging: Progress and Perspectives. BIOI. 2025. Vol. 6(1). DOI: 10.15212/bioi-2025-0047
22/10/2025 Compuscript Ltd
Regions: Europe, Ireland
Keywords: Health, Medical

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