The Neutrophil/Lymphocyte Ratio is Associated with Different Stages of Development of Coronary Artery Disease
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The Neutrophil/Lymphocyte Ratio is Associated with Different Stages of Development of Coronary Artery Disease

14/11/2022 Compuscript Ltd
Publication title: The Neutrophil/Lymphocyte Ratio is Associated with Different Stages of Development of Coronary Artery Disease
Author: Du, Jianlin
Publication type: Other
Publication date: 03/11/2022

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Inflammation plays a role in coronary artery disease (CAD). The neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR) and platelet/lymphocyte ratio (PLR) are blood parameters associated with inflammation. The authors of this article aimed to perform a systematic comparison and study the predictive values of these inflammatory parameters with respect to CAD stage. A total of 513 patients who had undergone coronary angiography (CAG) were retrospectively analyzed. Clinical status, lipid profiles, CAG scans and hematological parameters were collected. NLR, MLR and PLR were calculated. All patients were classified into a normal coronary group (n = 133), coronary atherosclerosis (CA) group (n = 149), chronic coronary syndrome (CCS) group (n = 175) or acute myocardial infarction (AMI) group (n = 56). NLR, MLR and PLR were compared among groups. NLR and MLR were higher in the CCS and AMI groups. PLR was higher in the AMI group. The AMI group had higher NLR, PLR and MLR than the CCS group. Logistic regression analysis revealed that NLR (OR:1.227, 95% CI: 1.016–1.482. P < 0.05) had a strong significant correlation with CAD. Area under the ROC curve of NLR was 0.580 (95% CI = 0.516–0.644) in predicting CCS and 0.727 (95% CI = 0.642–0.811) in predicting AMI. NLR may be associated with the occurrence and progression of CAD, and may serve as a marker of inflammation.

CVIA is available on the IngentaConnect platform and at Cardiovascular Innovations and Applications. Submissions may be made using ScholarOne Manuscripts. There are no author submission or article processing fees. CVIA is indexed in the EMBASE, ESCI, OCLC, Primo Central (Ex Libris), Sherpa Romeo, NISC (National Information Services Corporation), DOAJ and Index Copernicus Databases. Follow CVIA on Twitter @CVIA_Journal; or Facebook.

https://doi.org/10.15212/CVIA.2022.0018
The Neutrophil/Lymphocyte Ratio is Associated with Different Stages of Development of Coronary Artery Disease, Du, Jianlin, Cardiovascular Innovations and Applications, 2022, https://doi.org/10.15212/CVIA.2022.0018
14/11/2022 Compuscript Ltd
Regions: Europe, Ireland
Keywords: Health, Medical, Science, Life Sciences

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