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NTU Singapore scientists develop nanotech antimicrobial masks that can filter 99.9 per cent of bacteria, viruses, and haze particles

NTU Singapore scientists develop nanotech antimicrobial masks that can filter 99.9 per cent of bacteria, viruses, and haze particles

Materials scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a reusable “nanotech mask” that can filter out 99.9 per cent of bacteria, viruses and particulate matter (PM), as well as kill bacteria.

Its novel antimicrobial coating kills bacteria within 45 seconds and is effective for at least 144 hours (six days).

Its filtration efficiency surpasses those of N95 masks (95 per cent filtration of PM0.3) and can be washed and reused over 10 times.

In mid-May, Singapore tightened its Covid-19 measures as the country was facing an increase in the number of infections, and the population was advised to use face masks with high filtration capability to help curb the spread of the coronavirus.

The made-in-NTU mask comprises two key components: an antimicrobial coating made from copper nanoparticles developed and patented by Professor Lam Yeng Ming, coated on a fabric mask invented by Associate Professor Liu Zheng, which has a unique dielectric property that attracts all nanoparticles and germs.

Prof Lam, who is also the Chair of NTU’s School of Materials Science and Engineering, said their mask prototype combines the two most desired properties needed to fight COVID-19, into a single filter.

“In experiments, our copper nanoparticle coating has an extremely fast and sustained antibacterial activity, with a killing efficiency of up to 99.9 per cent when it meets multi-drug resistant bacteria. This coating will help to reduce the spread of bacteria as it kills microbes in droplets trapped by the mask fibres, which provide excellent filtration efficiency. This should give users a double layer of protection compared to conventional surgical masks,” explained Prof Lam.

Experiments on the antibacterial effectiveness of the mask were conducted in collaboration with scientists from the National University of Singapore (NUS). They simulated real-life conditions by introducing multi-drug resistant bacteria in droplet form onfabric surfaces and observed that almost all the bacteria were dead by 45 seconds.

The reason for the effectiveness of the antimicrobial coating was two-fold: the first is the extremely small size of the nanoparticles, which are about 1,000 times smaller than the width of a human hair. Collectively, millions of nanoparticles provide a huge surface area for the viruses and bacteria to contact, compared to bigger particles.

The second is the high level of oxidative damage caused by the copper oxide material. Copper oxide induces the generation of reactive oxygen species, resulting in DNA damage of important cell structures in the bacteria, such as the cell membrane, severely damaging it and causing the bacteria to die.

To make it easy to apply, the antimicrobial nanoparticle solution is designed to be spray-coated on all soft and hard surfaces.

Various peer-reviewed studies have shown that copper oxide is effective in killing viruses, such as the recent study published in ACS Applied Materials & Interfaces by The University of Hong Kong and Virginia Tech, where door handles were coated with a layer of copper oxide material. [1]

The NTU team tested their nanoparticle coating in harsh conditions for120 washing cycles(inthe presence of soap or its active componentsat 45 degC) and found that there was almost no copper loss – posing very little risk of toxicity to humans.
The nanoparticles are also bonded to the fibres within the mask, so there is no contact with human skin when the mask is worn.

Superior trapping capabilities of the mask

Killing viruses and bacteria would only work if the mask is able to trap and stop them from passing through. This is where Assoc Prof Liu’s breakthrough came in handy.

Last year, his team developed a way to integrate dielectric materials to plastic fibres during the manufacturing process of an unwoven fabric filter made from Polypropylene (PP), commonly used in disposable surgical masks used by hospitals. This was done in collaboration with Prof Guan Li from the Renmin University of China.

The dielectric materials have excellent electrostatic capabilities, which can attract and bind to particles possessing a negative or positive charge, similar to how magnets attract metal particles.

Made from fibres with a diameter of 200 to 300 nanometres, the mask has a higher surface area that lowers the breathing resistance – making it easy for its wearer to breathe as compared to conventional N95 respirators, which are denser.

In tests, the next-generation dielectric composite fabric had 50 per cent higher filtration efficiency than pure PP masks, which are commonly rated at 95 per cent BFE (Bacterial Filtration Efficiency).

Assoc Prof Liu said: “With our new composite filter, we can achieve up to 99.9 per cent BFE, trapping almost all microbes and particulate matter from smoke or haze. Its filtration efficiency surpasses a N95 mask but allows the wearer to breathe much easier.

“More importantly, it can be mass-produced easily using the current production process. It is also washable for more than 10 times before losing filtration efficiency, making it more sustainable than current one-use disposable masks.”

In experiments, the mask was able to attract and trap a broad range of particulate matter: from PM10 (average particle size of 10 microns) to PM0.3 (0.3 microns – about 0.3 per cent the diameter of a human hair) with a filtration efficiency of 99.9 per cent.

The antimicrobial coating has a patent filed through NTU’s enterprise and innovation company, NTUitive, and Prof Lam’s team is already working with a local company to coat it on their products.

Assoc Prof Liu’s dielectric composite fabric material is now used by an overseas manufacturer to make N95 masks that are as easy to breathe as disposable surgical masks and are available commercially.

The team is now looking to work with local industry partners who are keen to license and scale up the production of their 2-in-1 mask and are currently preparing scientific papers for submission in scientific journals.

NTU scientists have been working on developing solutions in the global fight against COVID-19.

These include innovations such as autonomous disinfection robots, COVID-19 rapid test kits and a breathalyser device, a smart mask, antimicrobial coatings, as well as fundamental research on the coronavirus to find new drug targets for treatment and vaccine development.

Healthcare is one of humanity’s grand challenges that NTU seeks to address under theNTU 2025 strategic plan.


About Nanyang Technological University, Singapore

A research-intensive public university, Nanyang Technological University, Singapore (NTU Singapore) has 33,000 undergraduate and postgraduate students in the Engineering, Business, Science, Humanities, Arts, & Social Sciences, and Graduate colleges. It also has a medical school, the Lee Kong Chian School of Medicine, established jointly with Imperial College London.
NTU is also home to world-renowned autonomous institutes – the National Institute of Education, S Rajaratnam School of International Studies, Earth Observatory of Singapore, and Singapore Centre for Environmental Life Sciences Engineering – and various leading research centres such as the Nanyang Environment & Water Research Institute (NEWRI) and Energy Research Institute @ NTU (ERI@N).

Ranked amongst the world’s top universities by QS, NTU has also been named the world’s top young university for the last seven years. The University’s main campus is frequently listed among the Top 15 most beautiful university campuses in the world and it has 57 Green Mark-certified (equivalent to LEED-certified) building projects, of which 95% are certified Green Mark Platinum. Apart from its main campus, NTU also has a campus in Singapore’s healthcare district.

Under the NTU Smart Campus vision, the University harnesses the power of digital technology and tech-enabled solutions to support better learning and living experiences, the discovery of new knowledge, and the sustainability of resources.

For more information, visit
Fichiers joints
  • Photo 3 – The N95 prototype mask made with dielectric fabric, with bottles of copper nanoparticles of various colours in the background.
  • (Clockwise from front right) Prof Lam Yeng Meng holding up copper nanoparticles in a solution; Assoc Prof Liu Zheng, holding up a N95 nanotech mask prototype; while Senior Research Fellow Dr Teddy Salim and Research Fellow Dr Rui Goncalves holding up the dielectric fabric that was used to make the mask prototypes that they are wearing.
  • Photo 2 – (L-R) Assoc Prof Liu Zheng holding the nanotech mask prototype with Prof Lam Yeng Meng holding the copper nanoparticles in a bottle.
Regions: Asia, Singapore, China
Keywords: Covid-19, Covid-19, Applied science, Engineering, Nanotechnology, Technology


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