Series explores the physiological and environmental considerations of aging in the context of cardiovascular disease

The JACC family of journals have published an eight-part series on chronological vs. biological aging in relation to heart health. The series of State-of-the-Art Reviews plus introductory commentary are featured across nine journals, including the Journal of the American College of Cardiology (JACC), JACC: Basic to Translation Science, JACC: Heart Failure, JACC: Cardiovascular Imaging, JACC: Clinical Electrophysiology, JACC: Asia, JACC: Advances, JACC: Cardiovascular Interventions and JACC: CardioOncology.

With a focus on cardiovascular disease (CVD), the series underscores the importance of understanding the distinction between chronological and biological aging and how biological factors influence CVD risk, progression and management, even when chronological years may not align. Clinical considerations that can affect the biological aging process and its impact on cardiovascular health are examined, including various biomarkers, genetic factors and lifestyle interventions, emphasizing the need and potential for tailored prevention and treatment strategies.

“There is much for caregivers and cardiovascular researchers to learn about how the linear passing of time from birth to old age, compared with how the accumulation of molecular and cellular changes result in a decline of cognitive and physiological function,” said JACC Editor-in-Chief Valentin Fuster, MD, MACC, in his introduction to the series.

The complete list of the JACC Journals Family Series on Chronological vs Biological Aging includes the following articles:

JACC
Chronological vs Biological Aging: JACC Journals Family Series (Introduction)
Valentin Fuster


JACC: Advances
TAVR in Older Adults: Moving Toward a Comprehensive Geriatric Assessment and Away From Chronological Age
Abdulla A. Damluji, Ashok Krishnaswami, et. al.


JACC: Asia
Impact of Aging on Cardiovascular Disease: From Chronological Observation to Biological Insights
Dong Zhao, Jian’an Wang, et. al.


JACC: Basic to Translational Science
Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications
Manish Kumar, Ming Xu, et. al.


JACC: CardioOncology
Cardiovascular Concerns, Cancer Treatment, and Biological and Chronological Aging in Cancer
Dina Ioffe, Efrat Dotan, et. al.


JACC: Cardiovascular Imaging
Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System
Zahra Raisi-Estabragh, Steffen E. Petersen, et. al.


JACC: Cardiovascular Interventions
Chronological vs Biological Age in Interventional Cardiology: A Comprehensive Approach to Care for Older Adults
Abdulla A. Damluji, Mohamad Alkhouli, et. al.


JACC: Clinical Electrophysiology
Assessing Biological Age: The Potential of ECG Evaluation Using Artificial Intelligence
Francisco Lopez-Jimenez, Zachi I. Attia, et. al.


JACC: Heart Failure
Aging in Heart Failure: Embracing Biology Over Chronology
Parag Goyal, Jason Roh, et. al.

View the full list of articles on JACC.org here. To request a copy of a paper, please email Olivia Walther at owalther@acc.org.

The American College of Cardiology (ACC) is the global leader in transforming cardiovascular care and improving heart health for all. As the preeminent source of professional medical education for the entire cardiovascular care team since 1949, ACC credentials cardiovascular professionals in over 140 countries who meet stringent qualifications and leads in the formation of health policy, standards and guidelines. Through its world-renowned family of JACC Journals, NCDR registries, ACC Accreditation Services, global network of Member Sections, CardioSmart patient resources and more, the College is committed to ensuring a world where science, knowledge and innovation optimize patient care and outcomes. Learn more at www.ACC.org or follow @ACCinTouch.

The ACC’s family of JACC Journals rank among the top cardiovascular journals in the world for scientific impact. The flagship journal, the Journal of the American College of Cardiology (JACC) — and family of specialty journals consisting of JACC: Advances, JACC: Asia, JACC: Basic to Translational Science, JACC: CardioOncology, JACC: Cardiovascular Imaging, JACC: Cardiovascular Interventions, JACC: Case Reports, JACC: Clinical Electrophysiology and JACC: Heart Failure — pride themselves on publishing the top peer-reviewed research on all aspects of cardiovascular disease. Learn more at JACC.org.

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