AI-Enabled Stethoscope Can Miss the Beat in Pets
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AI-Enabled Stethoscope Can Miss the Beat in Pets


Fourth-year veterinary students matched – and experienced clinicians outperformed – an AI-enabled digital stethoscope in diagnosing heart murmurs and arrhythmias in cats and dogs, according to a new study from North Carolina State University. The study emphasizes the importance of human expertise when using AI-assisted technology, particularly with instruments that are designed for “universal” usage.

“Stethoscopes are universal instruments – they’re designed to aid in auscultation, or listening to the heartbeat,” says Kursten Pierce, assistant professor of clinical sciences and board-certified cardiologist at NC State’s College of Veterinary Medicine. “Veterinarians use the same stethoscope as a human physician uses. These new AI-enabled stethoscopes are being adopted by many veterinarians, because they have a lot of very useful technical features, such as recording a heart murmur or an EKG.

“However, the diagnostic AI for these stethoscopes is trained on human data, not dog or cat data, and we were hearing from veterinarians who were second-guessing themselves based upon the stethoscope’s findings. So, we decided to look at an AI-enabled stethoscope’s diagnostic accuracy in dogs and cats.”

The research team performed auscultation on 105 companion animals: 54 dogs and 51 cats. Each animal was examined by a board-certified veterinary cardiologist, a cardiology resident, and a fourth-year veterinary student. The exams were conducted with an AI-enabled stethoscope, and the findings from the human experts were compared to the stethoscope’s findings.

In dogs, doctor assessment found that 38 (70%) had a murmur and 24 (44%) had an arrhythmia (abnormal heartbeat). Of the 38 dogs with a murmur, the AI software correctly identified 33 (87%). Fourth-year students matched the stethoscope’s performance exactly.

Arrhythmia detection told a very different story: the AI stethoscope never classified a single dog as free of an arrhythmia, and while it correctly flagged all 6 true cases of atrial fibrillation, it also mistakenly labeled 22 additional dogs as having atrial fibrillation when they did not.

In cats, doctor assessment found that 22 (43%) had a murmur and only one (2%) had an arrhythmia. The AI stethoscope diagnosed a murmur in only 2 of 51 cats – missing 20 of the true murmurs. Veterinary students performed substantially better in cats, correctly identifying murmurs in nearly two-thirds of affected cats.

“The most clinically concerning result to me was cats,” says Jake Johnson, cardiology resident at NC State and the first author of the research. “This device essentially couldn’t find a murmur, so a tool vets lean on for reassurance could let real disease go undetected – you wouldn’t necessarily think about the fact that the diagnostic algorithms are designed based on humans.

“We saw a similar pattern in dogs with arrhythmias: the stethoscope never once called a dog’s rhythm normal, and its atrial fibrillation calls were wrong three out of four times. That said, the ECG tracing it captures is genuinely good quality. This tool works best as an adjunct – a quick ECG or a flag worth a second look – not a stand-alone diagnosis.”

The researchers hope that their results will be used to encourage veterinarians and veterinary students to be better informed about the limitations of these stethoscopes in veterinary care.

“We want to encourage veterinarians to rely on the expertise they’ve gained through their training and to understand what this tool can and cannot provide in a veterinary setting, so that we continue to provide the best possible care to people and their companion animals,” Pierce says.

The study appears in the Journal of the American Veterinary Medical Association. Pierce is the corresponding author. Other NC State contributors are Joshua Stern, veterinary cardiologist and associate dean for research graduate studies, and Teresa DeFrancesco, professor of clinical sciences.

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Note to editors: An abstract follows.

“An artificial intelligence–enabled digital stethoscope demonstrates moderate murmur detection in dogs but not cats and unreliable arrhythmia classification in both species”

DOI: 10.2460/javma.26.05.0353

Authors: Jake Johnson, Joshua Stern, Teresa DeFrancesco, Kursten Pierce, North Carolina State University
Published: Aug. 5, 2026 in the Journal of the American Veterinary Medical Association

Abstract:
Objective
To prospectively evaluate the diagnostic performance of an AI-enabled digital stethoscope in detecting cardiac murmurs and arrhythmias compared to fourth-year veterinary students and experienced clinicians.
Methods
Dogs and cats presenting to a university teaching hospital were prospectively enrolled from August 1, 2025, through December 31, 2025. Each animal underwent a cardiac auscultation at 4 thoracic sites with the use of an AI-enabled digital stethoscope (Core 500; EKO Health Inc), 6-lead ECG, and echocardiogram, if clinically indicated. Auscultation was performed by a cardiology resident, board-certified cardiologist, and fourth-year veterinary student.
Results
The stethoscope demonstrated a sensitivity of 86.8%, specificity of 56.3%, and positive predictive value of 82.5% for murmur detection in dogs. There was no difference between the agreement of the AI stethoscope or students with a clinician (κ = 0.447). In cats, sensitivity was markedly lower (9.1%), with only 2 of 22 murmurs detected (κ = 0.081). The stethoscope demonstrated high sensitivity for atrial fibrillation (100%), but classified no dog as arrhythmia-free. Murmur grade was the only significant predictor of stethoscope murmur diagnosis, and high-grade murmurs (≥ 3) had significantly greater odds of detection (OR, 15.11).
Conclusions
The AI-enabled stethoscope demonstrated moderate murmur detection performance in dogs, comparable to fourth-year veterinary students, but performed poorly in cats. Arrhythmia classification was unreliable in both species.
Clinical Relevance
AI-enabled stethoscopes represent an emerging tool in veterinary medicine, but clinical validation is necessary before routine adoption. This study provides prospective performance data across small animals and examiner levels, identifying meaningful limitations regarding interpretation of this technology.
Regions: North America, United States
Keywords: Health, Medical

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