Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)
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Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)

05/05/2025 Compuscript Ltd
https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2025-0005
Announcing a new article publication for Zoonoses journal. Severe fever with thrombocytopenia syndrome (SFTS), caused by the tick-borne severe fever with thrombocytopenia syndrome virus (SFTSV), is a disease that is endemic to East Asia and has mortality rates reaching 30%. Despite its substantial public health impact, no vaccines or antiviral treatments are currently available. The SFTSV genome encodes key structural proteins, including glycoproteins (Gn and Gc) and nucleocapsid protein (NP), which serve as critical vaccine targets. This article reviews the current status of SFTSV-related vaccine platforms—such as viral vectors, inactivated viruses, DNA, mRNA, and protein-based approaches—and highlights the immune responses elicited by these platforms against key antigens, particularly glycoproteins and NP. Future research directions are additionally proposed to accelerate the development of effective SFTSV vaccines by leveraging insights from existing studies.
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eISSN 2737-7474
ISSN 2737-7466
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Hyo-Jin Ro and Nam-Hyuk Cho. Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV). Zoonoses. 2025. Vol. 5(1). DOI: 10.15212/ZOONOSES-2025-0005
Hyo-Jin Ro and Nam-Hyuk Cho. Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV). Zoonoses. 2025. Vol. 5(1). DOI: 10.15212/ZOONOSES-2025-0005
05/05/2025 Compuscript Ltd
Regions: Europe, Ireland
Keywords: Health, Medical

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