Hydrogel materials possess unique physicochemical properties, including high water absorption, strong moisture retention, biocompatibility, tunable mechanical properties, environmental responsiveness, biodegradability, and a three-dimensional network structure. These characteristics endow them with significant practical value and broad application prospects in fields such as tissue engineering and biomedicine.

Based on recent advances in related researches, Zhang et al. reviewed the applications of biomedical hydrogels in emerging areas such as tissue engineering, drug delivery systems, and wound dressings. The materials covered include natural polymer hydrogels, synthetic hydrogels, ceramic–polymer composites, and stimuli-responsive hydrogels. Additionally, they introduced hydrogel fabrication technologies and commercially available hydrogel-based products in the medical field. As part of the progress in tissue engineering applications, this review aims to provide a reference for further clinical development and application, which was reported by Frontiers of Materials Science.

DOI：10.1007/s11706-026-0763-2