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Archives of Physiology and Biochemistry : The Journal of Metabolic Diseases
08 August 2012
The pandemic prevalence of obesity represents a serious world-wide threat to public health, since obesity is a critical risk factor for major chronic diseases like cardiovascular disease and type 2 diabetes. The main objective of this COST Action was to advance our knowledge on the pathogenesis and prevention of obesity and the specific role of adipose tissue in the development of chronic complications associated with the metabolic syndrome.
This approach was driven by the hypothesis that adipose tissue is critically involved in transducing nutritional and environmental factors into endogenous mediators (adipokines), which promote the pathogenesis of major metabolic disorders. COST Action BM0602 was a multi-disciplinary network, joining scientists from divergent areas like clinical medicine, human physiology, cell and molecular biology, biochemistry, genetics and bioinformatics. This created a bench-to-bedside translational approach with a strong synergistic input to the research efforts.